Hypercum

Step 1: Hypercum Stimulates endothelial cells which results in release of NO(Nitric Oxide) Gas.

Step 2: NO gas released from endothelial cells, diffuses into smooth muscle cells that line small blood vessels.

Step 3: Once inside the smooth muscle cell, NO binds to an enzyme, called guanylate cyclase which esults in activation of guanylate cyclase.

Step 4: Guanylate cyclase being activated cleaves two phosphate groups from another compound called guanosine triphosphate . Which results in the formation of cyclic guanosine monophosphate.

Step 5: This cyclic guanosine monophosphate is responsible for phosphorylation of proteins,including the smooth muscle contractile protein called myosin.

Step 6: Once phosphorylation takes place, smooth muscle cell protien myosin relaxes, thus resulting in vasodilation of the vessel.